<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gomes, S. C.</style></author><author><style face="normal" font="default" size="100%">Abascal, C. C.</style></author><author><style face="normal" font="default" size="100%">Haas, A. N.</style></author><author><style face="normal" font="default" size="100%">Angst, P. D.</style></author><author><style face="normal" font="default" size="100%">Oppermann, R. V.</style></author><author><style face="normal" font="default" size="100%">Marcantonio, R. A.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Influence of supragingival biofilm control and smoking habit on Interleukin-1beta concentration</style></title><secondary-title><style face="normal" font="default" size="100%">Braz Oral Res</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">*Biofilms</style></keyword><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Dental Plaque/prevention &amp; control</style></keyword><keyword><style  face="normal" font="default" size="100%">Enzyme-Linked Immunosorbent Assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Gingival Crevicular Fluid/*chemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Interleukin-1beta/*analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Multivariate Analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontal Index</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontitis/*microbiology/*therapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Reference Values</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">Smoking/*adverse effects</style></keyword><keyword><style  face="normal" font="default" size="100%">Time Factors</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/26892351</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">1</style></number><edition><style face="normal" font="default" size="100%">2016/02/20</style></edition><volume><style face="normal" font="default" size="100%">29</style></volume><pages><style face="normal" font="default" size="100%">S1806-83242015000100302</style></pages><isbn><style face="normal" font="default" size="100%">1807-3107 (Electronic)1806-8324 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;This investigation compared gingival crevicular fluid (GCF) interleukin-1beta (IL-1beta) concentrations in periodontitis patients subjected to a strict supragingival biofilm control (Supra) for 6 months. Never-smokers (23) and smokers (n = 20; 19.6 +/- 11.8 cigarettes/day) moderate-to-severe chronic periodontitis patients underwent a 6 months period of supragingival control with weekly recall visits. Periodontal probing depth (PPD), bleeding on probing (BOP) and GCF samples (from different PPD category sites: 3-5 mm and 6-10 mm) were obtained at the baseline, 30, and 180 days. IL-1beta was assessed by enzyme-linked immunosorbent assay. Generalized estimating equations were used to fit prediction models of IL-1beta changes, considering the dependence between the examinations, and using only data from experimental sites. Overall IL-1beta concentrations decreased from 3.2 pg/microL to 1.9 pg/microL. Higher baseline IL-1beta concentrations were associated with higher baseline PPD values in both groups. There were no differences in IL-1beta concentrations between never-smokers and smokers over time for any PPD category. Higher baseline PPD values and the presence of BOP on day 180 were significantly associated with higher IL-1beta concentrations. A strict Supra regimen reduced IL-1beta concentrations over time in periodontitis patients. The benefits observed for smokers underline the importance of oral hygiene measures, even considering the presence of this important risk factor.&lt;/p&gt;
</style></abstract><accession-num><style face="normal" font="default" size="100%">26892351</style></accession-num><notes><style face="normal" font="default" size="100%">&lt;p&gt;Gomes, Sabrina CarvalhoAbascal, Carolina CoradiniHaas, Alex NogueiraAngst, Patricia Daniela MelchiorsOppermann, Rui VicenteMarcantonio, Rosemary Adriana ChiericiengComparative StudyBrazilBraz Oral Res. 2015;29(1):S1806-83242015000100302. doi: 10.1590/1807-3107BOR-2015.vol29.0115. Epub 2015 Oct 9.&lt;/p&gt;
</style></notes><auth-address><style face="normal" font="default" size="100%">Department of Periodontology, Dental School, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.Dental School, Universidade Luterana do Brasil, Canoas, RS, Brazil.Dental School, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.Department of Diagnoses and Surgery, Dental School, Universidade Estadual Paulista, Araraquara, SP, Brazil.</style></auth-address></record></records></xml>