<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kampits, C.</style></author><author><style face="normal" font="default" size="100%">Montenegro, M. M.</style></author><author><style face="normal" font="default" size="100%">Ribeiro, I. W.</style></author><author><style face="normal" font="default" size="100%">Furtado, M. V.</style></author><author><style face="normal" font="default" size="100%">Polanczyk, C. A.</style></author><author><style face="normal" font="default" size="100%">Rosing, C. K.</style></author><author><style face="normal" font="default" size="100%">Haas, A. N.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Periodontal disease and inflammatory blood cytokines in patients with stable coronary artery disease</style></title><secondary-title><style face="normal" font="default" size="100%">J Appl Oral Sci</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Biomarkers/blood</style></keyword><keyword><style  face="normal" font="default" size="100%">Coronary Artery Disease/*blood/physiopathology</style></keyword><keyword><style  face="normal" font="default" size="100%">Cross-Sectional Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Interferon-gamma/*blood</style></keyword><keyword><style  face="normal" font="default" size="100%">Interleukins/*blood</style></keyword><keyword><style  face="normal" font="default" size="100%">Linear Models</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontal Attachment Loss</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontal Diseases/*blood/physiopathology</style></keyword><keyword><style  face="normal" font="default" size="100%">Periodontal Index</style></keyword><keyword><style  face="normal" font="default" size="100%">Predictive Value of Tests</style></keyword><keyword><style  face="normal" font="default" size="100%">Reference Values</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">Smoking/adverse effects</style></keyword><keyword><style  face="normal" font="default" size="100%">Surveys and Questionnaires</style></keyword><keyword><style  face="normal" font="default" size="100%">Tumor Necrosis Factor-alpha/*blood</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jul-Aug</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/27556206</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">4</style></number><edition><style face="normal" font="default" size="100%">2016/08/25</style></edition><volume><style face="normal" font="default" size="100%">24</style></volume><pages><style face="normal" font="default" size="100%">352-8</style></pages><isbn><style face="normal" font="default" size="100%">1678-7765 (Electronic)1678-7757 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;MATERIAL AND METHODS: This cross-sectional study included 91 patients with stable CAD who had been under optimized cardiovascular care. Blood levels of IL-1beta, IL-6, IL-8, IL-10, IFN-gamma, and TNF-alpha were measured by Luminex technology. A full-mouth periodontal examination was conducted to record probing depth (PD) and clinical attachment (CA) loss. Multiple linear regression models, adjusting for gender, body mass index, oral hypoglycemic drugs, smoking, and occurre:nce of acute myocardial infarction were applied. RESULTS: CAD patients that experienced major events had higher concentrations of IFN-gamma (median: 5.05 pg/mL vs. 3.01 pg/mL; p=0.01), IL-10 (median: 2.33 pg/mL vs. 1.01 pg/mL; p=0.03), and TNF-alpha (median: 9.17 pg/mL vs. 7.47 pg/mL; p=0.02). Higher numbers of teeth with at least 6 mm of CA loss (R2=0.07) and PD (R2=0.06) were significantly associated with higher IFN-gamma log concentrations. Mean CA loss (R2=0.05) and PD (R2=0.06) were significantly related to IL-10 concentrations. Elevated concentrations of TNF-alpha were associated with higher mean CA loss (R2=0.07). CONCLUSION: Periodontal disease is associated with increased systemic inflammation in stable cardiovascular patients. These findings provide additional evidence supporting the idea that periodontal disease can be a prognostic factor in cardiovascular patients.&lt;/p&gt;
</style></abstract><accession-num><style face="normal" font="default" size="100%">27556206</style></accession-num><notes><style face="normal" font="default" size="100%">&lt;p&gt;Kampits, CassioMontenegro, Marlon MRibeiro, Ingrid W JFurtado, Mariana VPolanczyk, Carisi ARosing, Cassiano KHaas, Alex NengBrazilJ Appl Oral Sci. 2016 Jul-Aug;24(4):352-8. doi: 10.1590/1678-775720160082.&lt;/p&gt;
</style></notes><custom2><style face="normal" font="default" size="100%">PMC4990364</style></custom2><auth-address><style face="normal" font="default" size="100%">- Universidade Federal do Rio Grande do Sul, Faculdade de Odontologia, Departamento de Periodontia, Porto Alegre, RS, Brasil.- Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Divisao de Cardiologia, Porto Alegre, RS, Brasil.</style></auth-address></record></records></xml>